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Reports and evidence
     


Elimination of Engine Bleed Air Contamination (SAE - October, 1955)
 
EU Legislation Summaries - Consumer Safety
 
Air Quality in Airplane Cabins and Similar Enclosed Spaces (Martin B. Hocking, The Handbook of Environmental Chemistry) (Preview)
 
Material Data Safety Sheet - Tricresyl Phosphate
 
Organophosphate Exposure Research Papers by Prof. Mohamed B. Abou-Donia (1981 - 2008)
 
AUTOANTIBODIES TO NERVOUS SYSTEM-SPECIFIC PROTEINS ARE ELEVATED IN SERA OF FLIGHT CREW MEMBERS: BIOMARKERS FOR NERVOUS SYSTEM INJURY [Abstract] (Journal of Toxicology and Environmental Health)
 
Aerotoxic Syndrome Key Papers (1999 – Present)
 
Air Safety and Cabin Air Quality in the BAe 146 Aircraft Report (Australian Senate Report - October 2000)
 
NASA - ASRS Database Report - Cabin Smoke, Fire, Fumes, or Odor Incidents
 
GAPAN Summary Report - Health Effects of Contaminants in Aircraft Cabin Air by Prof. Michael Bagshaw
 
Press Release from Dr Sarah Myhill (ME/CFS)

3rd December 2012:

Discussion of the release of the paper: "Targeting mitochondrial dysfunction in the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - a clinical audit". Int J Clin Exp Med 2013;6 (1):1-15 Sarah Myhill, Norman E Booth, John McLaren-Howard

Click here to read the full press release

 
Neurobehavioral problems following low-level exposure to organophosphate pesticides: a systematic and meta-analytic review (Summary)
19th November 2012:

Meta-analysis was carried out to determine the neurotoxic effects of long-term exposure to low levels of organophosphates (OPs) in occupational settings. Concern about the effects of OPs on human health has been growing as they are increasingly used throughout the world for a variety of agricultural, industrial and domestic purposes. The neurotoxic effects of acute poisoning are well established but the possibility that low-level exposure causes ill health is controversial. It is important to get a clear answer to this question as more individuals are at risk of low-level exposure than acute poisoning. Although a number of reviews on this topic have been published in the past, authors have come to conflicting conclusions. To date, none of these reviews have attempted quantitative evaluation of study findings using meta-analysis.

Click here to read the full summary

Brain and nervous system damaged by low-level exposure to pesticides (UCL)

 
The Risks that Pesticdes Pose to Children by Becky Riley (October 2000)
 
Science Direct Article - Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants
 
Organophosphates in Aircraft Cabin and Cockpit Air — Method Development and Measurements of Contaminants
 
Assessing Aircraft Supply Air to Recommend Compounds for Timely Warning of Contamination - Richard Fox
 
Chronic Exposure To Organophosphates: Background and Clinical Picture
 
Collegium Basilea Cranfield Workshop report: from the Journal of Biological Physics and Chemistry
 
CASA Report: Contamination of Aircraft Cabin Air By Bleed Air
 
European Cockpit Association - "Cabin Air Contamination – A Safety Issue"
 
Organophosphate Poisoning by Dr Helen Fullerton
 
Boeing 787 Technical Explanation of Change of Air Supply

Click here to read the document (see highlighted text on pages 8 and 9)

 
Determination of Tricresyl Phosphate Air Contamination in Aircraft G. DENOLA, P. J. HANHELA and W. MAZUREK
 
Exposure to oil fumes on aircraft: necessary to regulate? By Judith Murawski
 
The “Aerotoxic Syndrome” — real condition or flight of fancy? By Jonathon Burdon
 
Reaction of Organophosphorous Agents in Aerotoxic Syndrome

Although we can't publish the full report, read the abstract here.

 
Exposure to tri-o-cresyl phosphate detected in jet airplane passengers

Although we can't publish the full report, read the abstract here

 
Case Study: Analysis of Reported Contaminated Air Events at One Major US Airline in 2009-10

Although we can't publish the full paper and evidence, you can read the abstract here.

 
Analysis of organophosphates in an air filter of a public transport aircraft
 
Crew effects from toxic exposures on aircraft 2005 Paper

"Crew effects from toxic exposures on aircraft"

A paper published in 2005 by Prof Chris Winder and Capt Susan Michaelis.

 

 
Aerotoxic Syndrome - First published paper

Aerotoxic Syndrome - health effects following exposure to jet oil mist during commercial flights.

The first published paper 4 - 6 September 2000

 ICOH 2000

 
EASA Cabin Air Quality on-board Large Aeroplanes

European Aviation Safety Agency

COMMENT RESPONSE DOCUMENT (CRD) TO ADVANCE NOTICE OF PROPOSED AMENDMENT (A-NPA) 2009-10

Executive summary

The Agency published the Advance Notice of Proposed Amendment (A-NPA) 2009-10, dated 28 September 2009, to initiate a discussion around a debate which deals with a specific source of cabin air quality degradation onboard Large Aeroplanes, i.e. air contamination by engine or Auxiliary Power Unit (APU).

 
Susan Michaelis, PhD

Susan Michaelis, PhD

Dr Susan Michaelis, Global Cabin Air Quality Executive head researcher and an Aerotoxic Syndrome sufferer has just been awarded a PhD in safety science on the subject “Health and Flight Implications From Exposure to Contaminated Air in Aircraft”. Susan has been working on the 975 page document for over ten years and has been awarded the highest possible grade. For her tireless dedication and for helping to bring the issue out into the open, the Aerotoxic Association says “Congratulations”!


 
Airborne Organophosphates in the Aviation Industry

PhD thesis

Airborne Organophosphates in the Aviation Industry. Sampling development and occupational exposure measurements.

by Kasper Flatland Solbu

This thesis is available for download at: http://op.solbu.no/

 
Medical aspects of work-related exposures to organophosphates (Guidance Note MS17)

This guidance document by the Health and Safety Executive (HSE) has information about the toxicology of organophosphates (OPs), acute and chronic symptoms, health monitoring, risk assessments, notification requirements following exposures and legal requirements of any organisations that may use these chemicals. We believe that no airlines are following any of the recommendations or adhering to any of the legal requirements. The HSE no longer publish this document and have been referring people to our site to obtain it.

PDF MS17, 1980                    PDF MS17, 1998 draft                    PDF MS17, 2000

 
Cabin air filtration solutions

Pall CorporationDespite the airlines and regulators insisting that filtering aircraft cabin air is still not technically possible, solutions do already exist and a limited number are already in operation on airliners.

Filter manufacturers Pall Corporation presented a paper at the 40th International Conference on Environmental Systems detailing various filtration solutions.

PDF Pall Corporation - Cabin air filtration systems

 
Development of diagnostics in the search for an explanation of Aerotoxic Syndrome

In his quest to develop a test to prove exposure to contaminated cabin air, Prof Clement Furlong and his lab have published this paper detailing progress on the test.

Biomarkers of organophosphorus (OP) exposures in humans

PDF Development of diagnostics in the search for an explanation of Aerotoxic Syndrome

Conference Poster: Biomarkers of organophosphorus (OP) exposures in humans

PDF Conference Poster: PDF version


 
An Attempt to Characterize the Frequency, Health Impact, and Operational Costs of Oil in the Cabin and Flight Deck Supply Air on U.S. Commercial Aircraft

“Industry, government, and labor representatives have all acknowledged that air supply systems on commercial aircraft sometimes get contaminated with pyrolyzed engine oil or hydraulic fluid, but efforts to define “sometimes” have been lacking.”

PDF Oil in the Cabin and Flight Deck Supply Air on U.S. Commercial Aircraft

 
European Aviation Safety Agency (EASA) Cabin Air Quality survey submissions

On 8th January 2010 the European Aviation Safety Agency (EASA) closed its survey on “Cabin Air Quality onboard Large Aeroplanes”. Here are some of the submissions:

 
Review of OPIN register of suspected OP - related health complaints

From the DEFRA website. Review of the Organophosphates Information Network (OPIN) register of suspected organophosphate – related health complaints. The register consists of farmers exposed to OPs, but the information in the documents may be of interest to aircrew and passengers exposed to OPs in contaminated cabin air.

 
Aerotoxic syndrome: a descriptive epidemiological survey of aircrew exposed to in-cabin airborne contaminants
 
Organophosphates report

This report from the Organophosphate Information Network (OPIN) discusses the familiar cycle of warnings, research, and conclusions calling for more research, which never leads to a resolution - going back as far as 1951. There are also some tragic accounts of victims affected by organophosphates. Report published in 2004

PDF OP report                    Word OP report from OPIN website

 
Professor Bagshaw's “The ‘Aerotoxic Syndrome’”

To provide an alternative viewpoint, here is an Aviation medical expert's view of Aerotoxic Syndrome, from September 2008. Please note: The Aerotoxic Association does not agree with Professor Bagshaw's views.

PDF The “Aerotoxic Syndrome” report

 
BAE Systems: Engine oil seals leak

In an All Operator Message, BAE Systems admits that oil gets into the cabins of their BAe 146 and Avro 146-RJ aircraft:

 
Identification and Characterization of Biomarkers of Organophosphorus (OP) Exposures in Humans
 
Interests and the shaping of an occupational health and safety controversy: the BAe 146 case

By Nickolas Vakas, University of Wollongong. “This thesis examines the controversy surrounding aircraft cabin air contaminated with oil. The focus is on the British Aerospace BAe 146 aircraft in Australia and the Australian Senate Inquiry which examined this aircraft.” Report conclusion: “The BAe 146, the most dangerous fume prone aircraft, should be grounded internationally”.

PDF Interests and the shaping of an occupational health and safety controversy: the BAe 146 case

Website

 
Neuropsychological and Psychiatric Functioning in Sheep Farmers Exposed to Organophosphate Pesticides

Prepared for DEFRA in the UK. This report is very relevant as it discusses organophosphates, which are present in jet engine oils. The symptoms suffered by aircrew, passengers and the sheep farming community are very similar. Of note is that DEFRA acknowledge there “may be” a link between exposure to the chemicals and neurological problems.

Word Neuropsychological and Psychiatric Functioning in Sheep Farmers Exposed to Organophosphate Pesticides

 
A survey of health symptoms in BALPA Boeing 757 pilots

Following numerous reports by its members that they were experiencing exposures to contaminated air supplies while at work, BALPA carried out a survey of its pilots.

PDF A survey of health symptoms in BALPA Boeing 757 pilots

 
Preliminary report on Aerotoxic Syndrome (AS) and the need for diagnostic neurophysiological tests

“Researchers have found, in studies carried out over several years, that many passengers and crew, following their recent flights in commercial jet aeroplanes, have become unwell, with a range of symptoms in common. This condition, which has not yet been officially recognised, is called Aerotoxic Syndrome (AS).”

PDF Preliminary report on Aerotoxic Syndrome                   PDF Report summary

 
The Toxicity of Commercial Jet Oils
 
Pilot Blood Test Results

Between March and May 2006 a group of 27 pilots in the UK took part in a study where blood samples were analysed for toxins and for damage to various bodily systems.

Excel Pilot Blood Test results                    PDF Pilot Blood Test results

 
Hazardous Chemicals on Jet Aircraft: Case Study - Jet Engine Oils and Aerotoxic Syndrome
 
Air Monitoring Studies for Aircraft Cabin Contamination
 
BALPA - Contaminated Air Protection - Air Safety and Cabin Air Quality

Proceedings of the BALPA Air Safety and Cabin Air Quality International Aero Industry Conference held at Imperial College, London, 20-21 April 2005.

PDF BALPA - Contaminated Air Protection conference proceedings

Aerotoxic Association article: BALPA - Then (2005) ... and Now

 
BAE Systems 146/RJ Service Information Leaflet 21-146-RJ-536-1 Cabin Air Quality Troubleshooting Advice and Relevant Modifications

Cabin Air Quality Troubleshooting Advice and Relevant Modifications.
Leaflet and Aerotoxic Association comment ...

 
Cognitive function following exposure to contaminated air on commercial aircraft

A case series of 27 pilots seen for clinical purposes. Published in the Journal of Nutritional & Environmental Medicine.

PDF Cognitive function following exposure to contaminated air on commercial aircraft

 
ExxonMobil Material Safety Data Sheet (MSDS) for Mobil Jet II

This is the most common oil used in jet engines.
Also available in other languages from the ExxonMobil website

Word ExxonMobil Mobil Jet Oil II MSDS

 
Tricresyl Phosphate (TCP) Material Safety Data Sheet (MSDS)

Aero engine oils such as Mobil Jet II contain 2-5% TCP

Tricresyl Phosphate (TCP) MSDS

 
Review of literature relating to the effects on humans of exposure to organophosphates
 
Extracts from actual AAIB (Air Accident Investigation Branch) reports

Crew accounts of the symptoms suffered after fume events.

PDF Extracts from actual AAIB reports

 
Ill health Following Exposure to Contaminated Aircraft Air: Psychosomatic Disorder or Neurological Injury?
 
Aerotoxic Syndrome - Notes to support Parliamentary Presentation June 18th 2007.

In a presentation to the UK Parliament in 2007, Malcolm Hooper stated his concern that the responsible authorities are using “obfuscation, deception and even downright lying” by trying to sustain the theory that Aerotoxic Syndrome is psychological in nature rather than neurological as a result of exposures to toxic aircraft cabin air.

 PDF Notes to support Parliamentary Presentation June 18th 2007

 
Government activity

Hansard - UK
Hansard is the daily updated record of questions and debates in the UK Houses of Parliament


Hansard - Australia

Questions and answers about cabin air quality in the Australian Senate and House of Representatives.


Government reports
UK House of Lords, UK Committee on Toxicity, FAA, CAA, NAS, UK Dept of Health, Australian Government including Senate report "Air Safety and Cabin Air Quality in the BAe 146 Aircraft"


Government recommendations
Including:
Australian Senate Enquiry into Air Safety
USA National Academy of Sciences to the FAA
UK House of Lords